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Case Reports
. 2021 Feb;47(2):838-842.
doi: 10.1111/jog.14584. Epub 2020 Dec 1.

COVID-19 in third trimester may not be as scary as you think, it can be innocent: Evaluating vertical transmission from a COVID-19 positive asymptomatic pregnant woman with early membrane rupture

Affiliations
Case Reports

COVID-19 in third trimester may not be as scary as you think, it can be innocent: Evaluating vertical transmission from a COVID-19 positive asymptomatic pregnant woman with early membrane rupture

Rabia M Palalioglu et al. J Obstet Gynaecol Res. 2021 Feb.

Abstract

In the literature, many cases of coronavirus disease 2019 (COVID-19) positive pregnancies have been observed, mostly with mild findings, but there is limited evidence about perinatal transition and early COVID-19 positive newborns. In this case, severe acute respiratory syndrome coronavirus 2 reverse transcription-polymerase chain reaction results were studied from samples obtained from the placenta, amniotic fluid, cord blood and postoperative breast milk - that were obtained while avoiding contamination and preserved appropriately - of a cesarean section performed under anesthesia on a woman with previous cesarean section and gestational diabetes mellitus history. This patient who presented to our emergency gynecology clinic with membrane rupture was infected with severe acute respiratory syndrome coronavirus 2 two weeks before delivery but was not treated as the disease was asymptomatic. In addition, literature data in line with this topic were evaluated to demonstrate that there was generally no perinatal transmission over 34 weeks of gestation.

Keywords: coronavirus disease 2019; pregnancy; reverse transcription-polymerase chain reaction; severe acute respiratory syndrome coronavirus 2; vertical transmission.

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Figures

Figure 1
Figure 1
Severe acute respiratory syndrome coronavirus 2 reverse transcription–polymerase chain reaction was negative in the breast milk, cord blood and amniotic fluid samples, respectively.
Figure 2
Figure 2
Chest computed tomography scans of asymptomatic patient.

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References

    1. Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019‐nCoV infecting pregnant women: Lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020; 12: 194. - PMC - PubMed
    1. WHO . Laboratory testing for 2019 novel coronavirus (2019‐nCoV) in suspected human cases. Interim guidance. 17 Jan 2020. [Cited 4 Feb 2020.] Available from URL: https://www.who.int/publications‐detail/laboratory‐testing‐for‐2019‐nove...
    1. Chen H, Guo J, Wang C et al. Clinical characteristics and intrauterine vertical transmission potential of COVID‐19 infection in nine pregnant women: A retrospective review of medical records. Lancet 2020; 395: 809–815. - PMC - PubMed
    1. Fuk‐Woo Chan J, Yuan S, Kok KH et al. A cluster of familial pneumonia associated with new coronavirus 2019 showing person‐to‐person transmission: Study of a family cluster. Lancet 2020; 395: 514–523. - PMC - PubMed
    1. Shi H, Han X, Jiang N et al. Radiological findings from 81 patients with COVID‐19 pneumonia in Wuhan, China: A descriptive study. Lancet Infect Dis 2020; 20: 425–434. - PMC - PubMed

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