Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

doi:10.1016/j.ijbiomac.2019.08.158

. 2019 Nov 1:140:808-824.

doi: 10.1016/j.ijbiomac.2019.08.158. Epub 2019 Aug 19.

Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

P Pathalamuthu¹, A Siddharthan², V R Giridev³, Victor Victoria⁴, Ramar Thangam⁵, Srinivasan Sivasubramanian⁴, Vincent Savariar⁴, T Hemamalini⁶

Affiliations

¹ Dept. of Mechanical Engineering, Anand Institute of Higher Technology, Chennai, India. Electronic address: pathalamuthup.mech@aiht.ac.in.
² Dept. of Production Engineering, Anna University, Chennai, India. Electronic address: sidharth@annauniv.edu.
³ Dept. of Textile Technology, Anna University, Chennai, India. Electronic address: vrgiridev@annauniv.edu.
⁴ Center for Environmental Research & Development, LIFE, Loyola College, Chennai, India.
⁵ CSIR-Central Leather Research Institute, Chennai, India.
⁶ Dept. of Textile Technology, Anna University, Chennai, India.

PMID: 31437502
DOI: 10.1016/j.ijbiomac.2019.08.158

Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

P Pathalamuthu et al. Int J Biol Macromol. 2019.

. 2019 Nov 1:140:808-824.

doi: 10.1016/j.ijbiomac.2019.08.158. Epub 2019 Aug 19.

Authors

P Pathalamuthu¹, A Siddharthan², V R Giridev³, Victor Victoria⁴, Ramar Thangam⁵, Srinivasan Sivasubramanian⁴, Vincent Savariar⁴, T Hemamalini⁶

Affiliations

¹ Dept. of Mechanical Engineering, Anand Institute of Higher Technology, Chennai, India. Electronic address: pathalamuthup.mech@aiht.ac.in.
² Dept. of Production Engineering, Anna University, Chennai, India. Electronic address: sidharth@annauniv.edu.
³ Dept. of Textile Technology, Anna University, Chennai, India. Electronic address: vrgiridev@annauniv.edu.
⁴ Center for Environmental Research & Development, LIFE, Loyola College, Chennai, India.
⁵ CSIR-Central Leather Research Institute, Chennai, India.
⁶ Dept. of Textile Technology, Anna University, Chennai, India.

PMID: 31437502
DOI: 10.1016/j.ijbiomac.2019.08.158

Abstract

Spirograph is a geometric drawing that produces mathematical roulette curves of the variety technically known as hypotrochoids and epitrochoids. This paper presents a research on a novel Spirograph Based Mechanical System (SBMS) meant for the production of electrospun mat with near uniform characteristics for wound dressing applications. A combination of natural (Chitosan) and artificial (Polyethylene oxide) polymer, along with Aloe vera plant extract has been evaluated as a material for wound dressing application. The improvement in the mechanical property, in vitro and in vivo studies indicate developed SBMS compared to the typical collectors has been found suitable for producing electrospun mat for wound dressing applications.

Keywords: Aloe vera; Chitosan; Electrospun mat; Mechanical property; Polyethylene oxide; Wound scaffold.

PubMed Disclaimer

Cited by

Therapeutic effects of electrospun chitosan nanofibers on animal skin wounds: A systematic review and meta-analysis.
Sánchez-Machado DI, Maldonado-Cabrera A, López-Cervantes J, Maldonado-Cabrera B, Chávez-Almanza AF. Sánchez-Machado DI, et al. Int J Pharm X. 2023 Mar 1;5:100175. doi: 10.1016/j.ijpx.2023.100175. eCollection 2023 Dec. Int J Pharm X. 2023. PMID: 36950662 Free PMC article. Review.
Encapsulation of Bioactive Compounds from Aloe Vera Agrowastes in Electrospun Poly (Ethylene Oxide) Nanofibers.
Solaberrieta I, Jiménez A, Cacciotti I, Garrigós MC. Solaberrieta I, et al. Polymers (Basel). 2020 Jun 10;12(6):1323. doi: 10.3390/polym12061323. Polymers (Basel). 2020. PMID: 32531945 Free PMC article.
Polymer-Based Scaffolds Loaded with Aloe vera Extract for the Treatment of Wounds.
Alven S, Khwaza V, Oyedeji OO, Aderibigbe BA. Alven S, et al. Pharmaceutics. 2021 Jun 26;13(7):961. doi: 10.3390/pharmaceutics13070961. Pharmaceutics. 2021. PMID: 34206744 Free PMC article. Review.
Antibacterial Aloe vera Based Biocompatible Hydrogel for Use in Dermatological Applications.
Chelu M, Musuc AM, Aricov L, Ozon EA, Iosageanu A, Stefan LM, Prelipcean AM, Popa M, Moreno JC. Chelu M, et al. Int J Mol Sci. 2023 Feb 15;24(4):3893. doi: 10.3390/ijms24043893. Int J Mol Sci. 2023. PMID: 36835300 Free PMC article.
Nanofiber Systems as Herbal Bioactive Compounds Carriers: Current Applications in Healthcare.
Huesca-Urióstegui K, García-Valderrama EJ, Gutierrez-Uribe JA, Antunes-Ricardo M, Guajardo-Flores D. Huesca-Urióstegui K, et al. Pharmaceutics. 2022 Jan 14;14(1):191. doi: 10.3390/pharmaceutics14010191. Pharmaceutics. 2022. PMID: 35057087 Free PMC article. Review.

See all "Cited by" articles

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

Affiliations

Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

Authors

Affiliations

Abstract

Similar articles

Cited by

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Abstract

Similar articles

Cited by

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources