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Review
. 2017 Jul-Aug;10(4):369-378.
doi: 10.1016/j.jiph.2016.08.007. Epub 2016 Sep 6.

Antibiotic resistance

Marianne Frieri  1 , Krishan Kumar  2 , Anthony Boutin  3
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Free article
Review

Antibiotic resistance

Marianne Frieri et al. J Infect Public Health. 2017 Jul-Aug.
Free article

Abstract

Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics. There is currently a shortage of effective therapies, lack of successful prevention measures, and only a few new antibiotics, which require development of novel treatment options and alternative antimicrobial therapies. Biofilms are involved in multidrug resistance and can present challenges for infection control. Virulence, Staphylococcus aureus, Clostridium difficile infection, vancomycin-resistant enterococci, and control in the Emergency Department are also discussed.

Keywords: Antibiotic resistance; Biofilms; Emergency Department; Infections; Public health.

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