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. 2015 Mar;35(2):242-5.
doi: 10.3343/alm.2015.35.2.242. Epub 2015 Feb 12.

Molecular characteristics of noroviruses genogroup I and genogroup II detected in patients with acute gastroenteritis

Heejin Ham  1 , Seah Oh  1 , Hyunjung Seung  1 , Sukju Jo  1
Affiliations

Molecular characteristics of noroviruses genogroup I and genogroup II detected in patients with acute gastroenteritis

Heejin Ham et al. Ann Lab Med. 2015 Mar.

Abstract

Noroviruses are the leading cause of epidemic gastroenteritis, including foodborne outbreak, in Korea. The prevalence of human noroviruses was studied in diarrheal stool samples of patients with acute gastroenteritis by conventional duplex reverse transcription (RT)-PCR. Diarrheal stool samples were collected from 1,685 patients from the local hospitals in Seoul. The prevalence of the noroviruses was 22.8% (222/972 patients) in 2012 and 11.2% (80/713 patients) in 2013, with a total of 17.9% (302/1,685 patients). Genotyping was performed on 302 norovirus-positive stool samples to reveal 5.6% prevalence of genogroup I (GI) (17/302) and 94.4% prevalence of genogroup II (GII) (285/302). The patients with norovirus-associated acute gastroenteritis mostly showed prevalence of GII norovirus, especially GII.4 (64.6%; 195/302).

Keywords: Acute gastroenteritis; GI; GII; GII.4; Norovirus; Prevalence.

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Conflict of interest statement

No potential conflicts of interest relevant to this article were reported.

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