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. 2013 Jan;41(Database issue):D1234-40.
doi: 10.1093/nar/gks1140. Epub 2012 Nov 24.

IPD--the Immuno Polymorphism Database

James Robinson  1 , Jason A Halliwell, Hamish McWilliam, Rodrigo Lopez, Steven G E Marsh
Affiliations

IPD--the Immuno Polymorphism Database

James Robinson et al. Nucleic Acids Res. 2013 Jan.

Abstract

The Immuno Polymorphism Database (IPD), http://www.ebi.ac.uk/ipd/ is a set of specialist databases related to the study of polymorphic genes in the immune system. The IPD project works with specialist groups or nomenclature committees who provide and curate individual sections before they are submitted to IPD for online publication. The IPD project stores all the data in a set of related databases. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of killer-cell immunoglobulin-like receptors, IPD-MHC, a database of sequences of the major histocompatibility complex of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTDAB, which provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterized melanoma cell lines. The data is currently available online from the website and FTP directory. This article describes the latest updates and additional tools added to the IPD project.

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Figures

Figure 1.
Figure 1.
The IPD Homepage provides access to the different IPD projects.
Figure 2.
Figure 2.
The B-Content Calculator allows you to enter the genotypes for up to five prospective donors and receive their assignments to one of three groups based on KIR B-Content. The groups refer to the associated relapse protection seen in a T-cell replete Unrelated Donor Hematopoietic Cell Transplant for Acute Myeloid Leukaemia.
Figure 3.
Figure 3.
A selection of fully sequenced KIR haplotypes, the IPD-KIR website provides an interactive graphic that illustrates the gene composition of a number of fully sequenced KIR haplotypes.
See this image and copyright information in PMC

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