Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Dec;12(12):835-48.
doi: 10.1038/nrc3397. Epub 2012 Nov 15.

Future directions in cancer prevention

Asad Umar  1 , Barbara K Dunn, Peter Greenwald
Affiliations
Review

Future directions in cancer prevention

Asad Umar et al. Nat Rev Cancer. 2012 Dec.

Abstract

Prevention of cancer remains the most promising strategy for reducing both its incidence and the mortality due to this disease. For more than four decades, findings from epidemiology, basic research and clinical trials have informed the development of lifestyle and medical approaches to cancer prevention. These include selective oestrogen receptor modulators and aromatase inhibitors for breast cancer, the 5-α-reductase inhibitors finasteride and dutasteride for prostate cancer, and the development of vaccines for viruses that are associated with specific cancers. Future directions include genetic, proteomic and other molecular approaches for identifying pathways that are associated with cancer initiation and development, as well as refining the search for immunologically modifiable causes of cancer.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. N Engl J Med. 2012 Sep 13;367(11):1002-11 - PubMed
    1. Lancet Infect Dis. 2010 Dec;10(12):845-52 - PubMed
    1. N Engl J Med. 2011 Feb 3;364(5):393-5 - PubMed
    1. J Biol Chem. 2008 Apr 18;283(16):10550-8 - PubMed
    1. J Bone Miner Res. 2011 Feb;26(2):397-404 - PubMed

MeSH terms

LinkOut - more resources