Abruption-associated prematurity
- PMID: 21890016
- PMCID: PMC3175371
- DOI: 10.1016/j.clp.2011.06.001
Abruption-associated prematurity
Abstract
Chronic, subacute decidual hemorrhage (ie, abruptio placenta and retrochorionic hematoma formation) is an important contributor to preterm parturition. Such hemorrhage induces thrombin from decidual tissue factor, which plays a pivotal role in the development of preterm premature rupture of membranes and preterm delivery by acting through protease-activated receptors to promote the production of pro-inflammatory cytokines, and matrix-degrading metalloproteinases. Severe, acute abruption can lead to maternal and fetal mortality. Current management of abruption is individualized based on severity of disease, underlying etiology, and gestational age.
Copyright © 2011 Elsevier Inc. All rights reserved.
Figures
Similar articles
-
Individualized treatment of preterm premature rupture of membranes to prolong the latency period, reduce the rate of preterm birth, and improve neonatal outcomes.Am J Obstet Gynecol. 2022 Aug;227(2):296.e1-296.e18. doi: 10.1016/j.ajog.2022.02.037. Epub 2022 Mar 5. Am J Obstet Gynecol. 2022. PMID: 35257664
-
Preterm premature rupture of membranes and abruptio placentae: is there an association between these pregnancy complications?Am J Obstet Gynecol. 1995 Feb;172(2 Pt 1):672-6. doi: 10.1016/0002-9378(95)90591-x. Am J Obstet Gynecol. 1995. PMID: 7856704
-
Histologic evidence of old intrauterine bleeding is more frequent in prematurity.Am J Obstet Gynecol. 1995 Oct;173(4):1065-70. doi: 10.1016/0002-9378(95)91327-0. Am J Obstet Gynecol. 1995. PMID: 7485294
-
Medically indicated--iatrogenic prematurity.Clin Perinatol. 2011 Sep;38(3):423-39. doi: 10.1016/j.clp.2011.06.002. Epub 2011 Jul 23. Clin Perinatol. 2011. PMID: 21890017 Review.
-
Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption.Thromb Res. 2009 Nov;124(5):516-20. doi: 10.1016/j.thromres.2009.07.017. Epub 2009 Aug 31. Thromb Res. 2009. PMID: 19720393 Free PMC article. Review.
Cited by
-
Chronic Abruptio Placentae With Multiple Alloantibodies: An Obstetrician's Challenge.Cureus. 2023 Oct 26;15(10):e47762. doi: 10.7759/cureus.47762. eCollection 2023 Oct. Cureus. 2023. PMID: 38021680 Free PMC article.
-
Placental abruption at near-term and term gestations: pathophysiology, epidemiology, diagnosis, and management.Am J Obstet Gynecol. 2023 May;228(5S):S1313-S1329. doi: 10.1016/j.ajog.2022.06.059. Epub 2023 Mar 23. Am J Obstet Gynecol. 2023. PMID: 37164498 Free PMC article. Review.
-
Single Nucleotide Polymorphisms from CSF2, FLT1, TFPI and TLR9 Genes Are Associated with Prelabor Rupture of Membranes.Genes (Basel). 2021 Oct 28;12(11):1725. doi: 10.3390/genes12111725. Genes (Basel). 2021. PMID: 34828331 Free PMC article.
-
Proteomic identification of novel plasma biomarkers associated with spontaneous preterm birth in women with preterm labor without infection/inflammation.PLoS One. 2021 Oct 28;16(10):e0259265. doi: 10.1371/journal.pone.0259265. eCollection 2021. PLoS One. 2021. PMID: 34710180 Free PMC article.
-
Using Satellite-Based Spatiotemporal Resolved Air Temperature Exposure to Study the Association between Ambient Air Temperature and Birth Outcomes in Massachusetts.Environ Health Perspect. 2015 Oct;123(10):1053-8. doi: 10.1289/ehp.1308075. Epub 2015 Apr 7. Environ Health Perspect. 2015. PMID: 25850104 Free PMC article.
References
-
- Martin JA, Osterman MJ, Sutton PD. Are preterm births on the decline in the United States? Recent data from the National Vital Statistics System. NCHS Data Brief. 2010;39(39):1–8. - PubMed
-
- Behrman RE, Butler AS. Societal Costs of Prematurity. In: Behrman RE, Butler AS, editors. Preterm Birth: Causes, Consequences, and Prevention. Washington DC: National Academies Press; 2007. pp. 398–429. - PubMed
-
- Ananth CV, Berkowitz GS, Savitz DA, et al. Placental abruption and adverse perinatal outcomes. JAMA. 1999;282(17):1646–51. - PubMed
-
- Williams MA, Mittendorf R, Lieberman E, et al. Adverse infant outcomes associated with first-trimester vaginal bleeding. Obstet Gynecol. 1991;78(1):14–8. - PubMed
-
- Harger JH, Hsing AW, Tuomala RE, et al. Risk factors for preterm premature rupture of fetal membranes: a multicenter case-control study. Am J Obstet Gynecol. 1990;163(1 Pt 1):130–7. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical