Prevalence of rotavirus, adenovirus, norovirus, and astrovirus infections and coinfections among hospitalized children in northern France
- PMID: 20305010
- PMCID: PMC2863921
- DOI: 10.1128/JCM.02181-09
Prevalence of rotavirus, adenovirus, norovirus, and astrovirus infections and coinfections among hospitalized children in northern France
Abstract
From January to December 2007, 973 stool specimens were prospectively collected from children hospitalized for gastroenteritis signs or from neonates and premature cases who were born in two French hospital settings in the north of France. They were tested by rapid enzyme immunoassay (EIA) analyses for rotavirus and adenovirus and by two commercially available ELISA tests for the detection of norovirus and astrovirus. The overall rates of prevalence for rotavirus, norovirus, adenovirus, and astrovirus were 21, 13, 5, and 1.8%, respectively, and they did not significantly differ between the two hospital settings (P=0.12). Mixed virus infections were detected in 32 (3.3%) of the 973 study children and were associated with norovirus in 21 (66%) infants, including 5 premature cases. From fall to spring, norovirus infections accounted for 52% of documented gastroenteritidis viral infections at a time when rotavirus was epidemic, resulting in mixed norovirus and rotavirus gastrointestinal tract infections. Of the 367 documented viral gastroenteritis cases, 15 (4.1%) were identified as nosocomial infections, 5 of which occurred in premature cases. These findings highlight the need to implement norovirus and astrovirus ELISA detection assays in association with rapid EIA rotavirus and adenovirus detection assays for the clinical diagnosis and the nosocomial prevention of gastroenteritis viral infections in pediatric departments.
Figures
Similar articles
-
A molecular study on the prevalence and coinfections of Rotavirus, Norovirus, Astrovirus and Adenovirus in children with gastroenteritis.Minerva Pediatr. 2019 Oct;71(5):431-437. doi: 10.23736/S0026-4946.16.04304-X. Minerva Pediatr. 2019. PMID: 31660711
-
Prevalence of group A rotavirus, human calicivirus, astrovirus, and adenovirus type 40 and 41 infections among children with acute gastroenteritis in Dijon, France.J Clin Microbiol. 1999 Sep;37(9):3055-8. doi: 10.1128/JCM.37.9.3055-3058.1999. J Clin Microbiol. 1999. PMID: 10449507 Free PMC article.
-
Astrovirus, adenovirus, and rotavirus in hospitalized children: prevalence and association with gastroenteritis.J Pediatr Gastroenterol Nutr. 2002 Jul;35(1):64-8. doi: 10.1097/00005176-200207000-00014. J Pediatr Gastroenterol Nutr. 2002. PMID: 12142812
-
[Acute viral gastroenteritis in children].Wiad Lek. 2006;59(7-8):534-7. Wiad Lek. 2006. PMID: 17209354 Review. Polish.
-
Developments in understanding acquired immunity and innate susceptibility to norovirus and rotavirus gastroenteritis in children.Curr Opin Pediatr. 2015 Feb;27(1):105-9. doi: 10.1097/MOP.0000000000000166. Curr Opin Pediatr. 2015. PMID: 25490691 Free PMC article. Review.
Cited by
-
Molecular analysis of adenovirus strains responsible for gastroenteritis in children, under five, in Tunisia.Heliyon. 2023 Nov 30;10(1):e22969. doi: 10.1016/j.heliyon.2023.e22969. eCollection 2024 Jan 15. Heliyon. 2023. PMID: 38163238 Free PMC article.
-
Diverse genotypes of human enteric and non-enteric adenoviruses circulating in children hospitalized with acute gastroenteritis in Thailand, from 2018 to 2021.Microbiol Spectr. 2023 Aug 17;11(5):e0117323. doi: 10.1128/spectrum.01173-23. Online ahead of print. Microbiol Spectr. 2023. PMID: 37589466 Free PMC article.
-
Epidemiology of gastrointestinal infections: lessons learned from syndromic testing, Region Zealand, Denmark.Eur J Clin Microbiol Infect Dis. 2023 Sep;42(9):1091-1101. doi: 10.1007/s10096-023-04642-5. Epub 2023 Jul 19. Eur J Clin Microbiol Infect Dis. 2023. PMID: 37468662 Free PMC article.
-
Surveillance and epidemiological characterization of human adenovirus infections among outpatient children with acute gastroenteritis during the COVID-19 epidemic in Shanghai, China.Virol J. 2023 Jun 21;20(1):133. doi: 10.1186/s12985-023-02105-z. Virol J. 2023. PMID: 37344873 Free PMC article.
-
The role of viruses in human acute appendicitis: a systematic literature review.Int J Colorectal Dis. 2023 Apr 18;38(1):102. doi: 10.1007/s00384-023-04391-z. Int J Colorectal Dis. 2023. PMID: 37069433 Review.
References
-
- Bagci, S., A. M. Eis-Hübinger, A. R. Franz, G. Bierbaum, A. Heep, O. Schildgen, P. Bartmann, B. Kupfer, and A. Mueller. 2008. Detection of astrovirus in premature infants with necrotizing enterocolitis. Pediatr. Infect. Dis. J. 27:347-350. - PubMed
-
- Berner, R., R. F. Schumacher, S. Hameister, and J. Forster. 1999. Occurrence and impact of community-acquired and nosocomial rotavirus infections—a hospital-based study over 10 y. Acta Paediatr. Suppl. 88:48-52. - PubMed
-
- de Wit, M. A., M. P. Koopmans, L. M. Kortbeek, W. J. Wannet, J. Vinje, F. van Leusden, A. I. Bartelds, and Y. T. van Duynhoven. 2001. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. Am. J. Epidemiol. 154:666-674. - PubMed
-
- Harada, S., M. Okada, S. Yahiro, K. Nishimura, S. Matsuo, J. Miyasaka, R. Nakashima, Y. Shimada, T. Ueno, S. Ikezawa, K. Shinozaki, K. Katayama, T. Wakita, N. Takeda, and T. Oka. 2009. Surveillance of pathogens in outpatients with gastroenteritis and characterization of sapovirus strains between 2002 and 2007 in Kumamoto Prefecture, Japan. J. Med. Virol. 81:1117-1127. - PubMed
-
- Hunter, C. J., J. S. Upperman, H. R. Ford, and V. Camerini. 2008. Understanding the susceptibility of the premature infant to necrotizing enterocolitis (NEC). Pediatr. Res. 63:117-123. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical