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. 2009;16(11):1379-85.
doi: 10.2174/092986609789353754.

Surface Plasmon Resonance Imaging sensor for cathepsin determination based on immobilized cystatin

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Surface Plasmon Resonance Imaging sensor for cathepsin determination based on immobilized cystatin

E Gorodkiewicz. Protein Pept Lett. 2009.

Abstract

A specific SPRI sensor for cathepsin determination based on the interaction between immobilized cystatin and cathepsins has been developed. All cathepsins form the same calibration curve. The sensor dynamic response range is between 0.5 and 2.0 ng ml(-1) and the detection limit is equal to 0.1 ng ml(-1).

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