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. 2008 Mar 19;582(6):943-8.
doi: 10.1016/j.febslet.2008.02.037. Epub 2008 Feb 25.

Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

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Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

Yael Galon et al. FEBS Lett. .
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Abstract

Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

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