doi: 10.1017/s1092852900012797.
Clinical management of alcohol withdrawal
Affiliations
- PMID: 18296996
- DOI: 10.1017/s1092852900012797
Item in Clipboard
Clinical management of alcohol withdrawal
CNS Spectr.
2000 Feb.
Abstract
It has been well known for a number of years that abrupt withdrawal from alcohol following chronic use is associated with adverse consequences, ranging from mild tremors to withdrawal seizures. The overall purposes of treating alcohol withdrawal (AW) are to relieve patient discomfort, to prevent the development of more serious withdrawal symptoms, and to initiate long-term alcohol rehabilitation. Several areas of controversy exist in the clinical management of AW, including the optimal treatment setting, the need for pharmacologic management, and the most appropriate agent to prescribe when medication is deemed necessary. This article reviews the clinical features, general management, and treatment of AW.
Similar articles
-
Natriuretic peptides in alcohol withdrawal: central and peripheral mechanisms.Curr Med Chem. 2003 Dec;10(23):2559-76. doi: 10.2174/0929867033456459. Curr Med Chem. 2003. PMID: 14529471 Review.
-
Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms.J Clin Psychopharmacol. 2009 Aug;29(4):334-42. doi: 10.1097/JCP.0b013e3181aba6a4. J Clin Psychopharmacol. 2009. PMID: 19593171 Clinical Trial.
-
Pharmacotherapies for alcohol abuse. Withdrawal and treatment.Med Clin North Am. 1997 Jul;81(4):881-907. doi: 10.1016/s0025-7125(05)70554-x. Med Clin North Am. 1997. PMID: 9222259 Review.
-
Alcohol withdrawal syndrome: how to predict, prevent, diagnose and treat it.Prescrire Int. 2007 Feb;16(87):24-31. Prescrire Int. 2007. PMID: 17323538
-
Assessment of the role of kindling in the pathogenesis of alcohol withdrawal seizures and delirium tremens.Alcohol Clin Exp Res. 1999 Feb;23(2):204-8. Alcohol Clin Exp Res. 1999. PMID: 10069546 Clinical Trial.
Cited by
-
Alcohol withdrawal symptoms predict corticostriatal dysfunction that is reversed by prazosin treatment in alcohol use disorder.Addict Biol. 2022 Mar;27(2):e13116. doi: 10.1111/adb.13116. Epub 2021 Dec 2. Addict Biol. 2022. PMID: 34856641 Free PMC article. Clinical Trial.
-
Effective Reduction of Acute Ethanol Withdrawal by the Tetracycline Derivative, Tigecycline, in Female and Male DBA/2J Mice.Alcohol Clin Exp Res. 2016 Dec;40(12):2499-2505. doi: 10.1111/acer.13259. Epub 2016 Nov 14. Alcohol Clin Exp Res. 2016. PMID: 27862011 Free PMC article.
-
Stress and substance use disorders: risk, relapse, and treatment outcomes.J Clin Invest. 2024 Aug 15;134(16):e172883. doi: 10.1172/JCI172883. J Clin Invest. 2024. PMID: 39145454 Free PMC article. Review.
-
Intermittent hypoxia training: Powerful, non-invasive cerebroprotection against ethanol withdrawal excitotoxicity.Respir Physiol Neurobiol. 2018 Oct;256:67-78. doi: 10.1016/j.resp.2017.08.007. Epub 2017 Aug 12. Respir Physiol Neurobiol. 2018. PMID: 28811138 Free PMC article. Review.