doi: 10.1016/j.tibtech.2006.10.001.
Epub 2006 Oct 12.
The validity of predicted T-cell epitopes
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- PMID: 17045685
- DOI: 10.1016/j.tibtech.2006.10.001
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The validity of predicted T-cell epitopes
Trends Biotechnol.
2006 Dec.
Abstract
High-performing MHC class I binding predictions have been available for more than a decade; however, their value in terms of actual epitope finding has only now been estimated in a large-scale investigation undertaken by the group of Sette. This work underlines the importance of bioinformatics as a resource-saving tool in the field of epitope discovery. In addition, the data can be used to benchmark the performance of other new or existing CTL epitope-prediction tools.
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