Review
doi: 10.1038/nrm1703.
Transcriptional regulation and transformation by Myc proteins
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- PMID: 16064138
- DOI: 10.1038/nrm1703
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Review
Transcriptional regulation and transformation by Myc proteins
Nat Rev Mol Cell Biol.
2005 Aug.
Abstract
Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.
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