Case Reports
doi: 10.1086/426078.
Epub 2004 Nov 19.
Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy
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- PMID: 15578411
- DOI: 10.1086/426078
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Case Reports
Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy
Clin Infect Dis.
.
Abstract
Rapidly progressive Kaposi sarcoma (KS) lesions with lymphadenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4(+) lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4(+) lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.
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