Table 1
Rome 1963 [6] | New York 1966 [7] | ARA preliminary classification criteria for acute gout 1977 [5] | |
Items |
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|
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Case definition | Two or more of any criteria | Two or more of any criteria OR presence of MSU crystals in SF or on deposition | Six of 12 clinical criteria required OR presence of MSU crystals in SF or in tophus |
Limitations of these criteria | Developed based on expert opinion | Physician diagnosis considered to be the gold standard. MSU crystal identification was not used to define cases during development process. | |
Controls limited to patients with RA, acute calcium pyrophosphate crystal arthritis and acute septic arthritis—common mimickers such as OA, PsA, and reactive arthritis excluded. | |||
SF examination performed in only 51 % of gout patients and in 47 % of the controls. Of the gout patients that underwent synovial analysis, only 84 % had MSU crystals identified. | |||
Developed prior to availability of advanced imaging modalities. |
ARA American Rheumatism Association, MSU monosodium urate, SF synovial fluid, MTP metatarsophalangeal, SD standard deviations, RA rheumatoid arthritis, OA osteoarthritis, PsA psoriatic arthritis