Abstract
Prosthetic valve endocarditis (PVE) is a grave medical entity with potentially fatal end results. The disease encompasses a rather small but, in the same time, vital part of IE incidents that is probable to be augmented in future years. PVE occurs in 1-4% of valve recipients during the first year following valve replacement, and in approximately 1 % per year afterwards. The type of prosthetic valve (mechanical versus bioprosthetic) seems not having an impact on the rate of development of IE and it is comparable in both groups (0.8 cases per year of follow-up). The pathogenetic mechanisms, pathogens implicated, clinical features and diagnostic approach of PVE will be reviewed here, along with the antibacterial and potential surgical treatment and prevention of the disease.
Cardiovascular & Hematological Disorders-Drug Targets
Title: Prosthetic Valve Endocarditis: Diagnostic Approach and Treatment Options
Volume: 9 Issue: 4
Author(s): Ioannis Starakis and Elias E. Mazokopakis
Affiliation:
Abstract: Prosthetic valve endocarditis (PVE) is a grave medical entity with potentially fatal end results. The disease encompasses a rather small but, in the same time, vital part of IE incidents that is probable to be augmented in future years. PVE occurs in 1-4% of valve recipients during the first year following valve replacement, and in approximately 1 % per year afterwards. The type of prosthetic valve (mechanical versus bioprosthetic) seems not having an impact on the rate of development of IE and it is comparable in both groups (0.8 cases per year of follow-up). The pathogenetic mechanisms, pathogens implicated, clinical features and diagnostic approach of PVE will be reviewed here, along with the antibacterial and potential surgical treatment and prevention of the disease.
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Cite this article as:
Starakis Ioannis and Mazokopakis E. Elias, Prosthetic Valve Endocarditis: Diagnostic Approach and Treatment Options, Cardiovascular & Hematological Disorders-Drug Targets 2009; 9 (4) . https://dx.doi.org/10.2174/1871529X10909040249
DOI https://dx.doi.org/10.2174/1871529X10909040249 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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Effective Lowering pf Lipoprotein (a) – A new Frontier in Cardiovascular Risk Reduction
Elevated lipoprotein(a) (Lp[a]) is a genetically determined cardiovascular risk factor, causally linked to both atherosclerotic coronary artery disease and aortic valve stenosis. Elevated Lp(a) is widely prevalent, and several cardiovascular societies now recommend performing Lp(a) screening at least once in all adults. While, there are currently no approved drugs aimed ...read more
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