Abstract
Background: Cardiovascular diseases (CVD) are the number one cause of death globally compared to any other cause. CVD accounts for approximately 17.3 million deaths per year and are rising. Hypertension is the leading risk factor for cardiovascular diseases. Approximately, 80 million people suffer from hypertension in the U.S. While, majority of these individuals are on antihypertensive medications only 54% of individuals with hypertension are optimally controlled. Heart failure and stroke are some of the devastating complications of uncontrolled hypertension. Hypertensive crisis can be classified as either an urgency or emergency; difference between the two is the presence of end organ damage, which is noted in hypertensive emergency. Hypertensive crisis is usually treated by parenteral antihypertensive medications. The main drug classes of drugs for treatment are nitrates, calcium channel blockers, dopamine-1 agonists, adrenergic-blocking agents etc.
Conclusion: In this review, we discuss approach to management of hypertensive crisis and each drug class with its physiology and complications.Keywords: Hypertensive emergency, cardiovascular disease, antihypertensive medications, pregnancy, eclampsia.
Cardiovascular & Hematological Disorders-Drug Targets
Title:Guide of Hypertensive Crisis Pharmacotherapy
Volume: 17 Issue: 1
Author(s): Priyanka Wani-Parekh*, Carlos Blanco-Garcia, Melissa Mendez and Debabrata Mukherjee
Affiliation:
- Department of Internal Medicine, Texas Tech University Health Science Center at El Paso, Paul L. Foster School of Medicine, 4800 Alberta Ave, El Paso, Texas, 79905,United States
Keywords: Hypertensive emergency, cardiovascular disease, antihypertensive medications, pregnancy, eclampsia.
Abstract: Background: Cardiovascular diseases (CVD) are the number one cause of death globally compared to any other cause. CVD accounts for approximately 17.3 million deaths per year and are rising. Hypertension is the leading risk factor for cardiovascular diseases. Approximately, 80 million people suffer from hypertension in the U.S. While, majority of these individuals are on antihypertensive medications only 54% of individuals with hypertension are optimally controlled. Heart failure and stroke are some of the devastating complications of uncontrolled hypertension. Hypertensive crisis can be classified as either an urgency or emergency; difference between the two is the presence of end organ damage, which is noted in hypertensive emergency. Hypertensive crisis is usually treated by parenteral antihypertensive medications. The main drug classes of drugs for treatment are nitrates, calcium channel blockers, dopamine-1 agonists, adrenergic-blocking agents etc.
Conclusion: In this review, we discuss approach to management of hypertensive crisis and each drug class with its physiology and complications.Export Options
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Cite this article as:
Wani-Parekh Priyanka*, Blanco-Garcia Carlos , Mendez Melissa and Mukherjee Debabrata, Guide of Hypertensive Crisis Pharmacotherapy, Cardiovascular & Hematological Disorders-Drug Targets 2017; 17 (1) . https://dx.doi.org/10.2174/1871529X16666161220142020
DOI https://dx.doi.org/10.2174/1871529X16666161220142020 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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