Microarray Studies in Understanding the Mechanism of Action of Antiepileptic Drugs

Title:Microarray Studies in Understanding the Mechanism of Action of Antiepileptic Drugs

Volume: 1

Author(s): Lilach Toker, RH Belmaker and Galila Agam

Affiliation:

Keywords: Epilepsy, anticonvulsants, microarrays, mood-stabilizers, Epileptic Tissue, Cytoprotection, gene expression, multiple sclerosis, inhibitory synapses, mood-stabilizing drugs, glutamate-induced apoptotic cell death, Antidepressants, ectopic granule cells, mood disorders, GABAergic dysfunction

Abstract: In the present review we integrated findings from microarray analyses of anticonvulsant treatment, discussing the replicability of the findings and their corroboration with data obtained from patients and with information from other fields of study. We further relate to the duality of several antiepileptic drugs exhibiting both anticonvulsant and moodstabilizing effects in the treatment of epilepsy and bipolar disorder, respectively.

Cite this article as:

Toker Lilach, Belmaker RH and Agam Galila, Microarray Studies in Understanding the Mechanism of Action of Antiepileptic Drugs, Current Psychopharmacology 2012; 1 (4) . https://dx.doi.org/10.2174/2211556011201040327