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820
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169
replies
157k
views
110 follow
News: The Biostar Handbook. A bioinformatics e-book for beginners.
training handbook
updated 6 weeks ago by 3.0k • written 7.9 years ago by 101k
122
votes
44
replies
12k
views
24 follow
News: Help Make Biostar Better! Add Your Feedback, Opinions And Suggestions.
meta biostars
updated 12 months ago by 44k • written 11.9 years ago by 101k
81
votes
39
replies
8.3k
views
11 follow
News: State Of Biostar - Future Directions (January 2013)
biostars
updated 20 months ago by 44k • written 11.8 years ago by 101k
59
votes
31
replies
5.4k
views
12 follow
News: Example of how bioinformaticians can publish in Scientific Reports (by nature publishing group) using publicly available NGS data
publication NGS
updated 18 months ago by 44k • written 7.8 years ago by 11k
57
votes
24
replies
6.9k
views
14 follow
News: Join us in building a bioinformatics resource: The Biostar Handbook
biostar-handbook
updated 2.1 years ago by 44k • written 9.1 years ago by 101k
54
votes
24
replies
4.5k
views
12 follow
News: Big news from Microsoft. BASH on windows.
windows
updated 19 months ago by 44k • written 8.6 years ago by ★ 3.2k
51
votes
17
replies
4.3k
views
News: Biostars 3.0 is now under testing. It has groups, charms and other interesting features.
meta biostars
updated 20 months ago by 44k • written 9.6 years ago by 101k
48
votes
13
replies
26k
views
10 follow
News: The New Grch38 Human Genome Browser Has Arrived!
ucsc assembly GRCh38 hg38
updated 2.8 years ago by 44k • written 10.7 years ago by 28k
46
votes
16
replies
6.2k
views
12 follow
News: Google announces DeepVariant
genome deep-learning google
updated 17 months ago by 44k • written 6.9 years ago by ▴ 990
45
votes
19
replies
6.9k
views
8 follow
News: Gamestorming For Bioinformatics
gamestorming
updated 20 months ago by 44k • written 12.1 years ago by 28k
38
votes
7
replies
2.6k
views
News: 2 last seats available - 7th Berlin Summer School in NGS Data Analysis (September 4-8 in Berlin)
Transcriptomics DNA-Seq Variant-Calling RNA-Seq
15 months ago by David Langenberger 11k
38
votes
8
replies
1.9k
views
6 follow
News: What happens when a bioinformatician has his own genome sequenced for $300?
DNAseq DNA WGS
updated 16 months ago by 35k • written 16 months ago by 11k
33
votes
5
replies
3.9k
views
News: FINAL CALL: Epigenetics Workshop - DNA Methylation Data Analysis (some last seats available)
Epigenetics Workshop Bisulfite-Sequencing
updated 19 months ago by 44k • written 8.4 years ago by ▴ 460
33
votes
4
replies
7.0k
views
News: Rosalind: A Novel Bioinformatics Education Platform
education
updated 20 months ago by 44k • written 12.1 years ago by ▴ 330
32
votes
6
replies
14k
views
7 follow
News: Ncbi Releases Entrez Direct, The Entrez Utilities On The Unix Command Line
ncbi genbank pubmed command-line entrez
updated 20 months ago by 44k • written 10.7 years ago by 164k
27
votes
7
replies
3.8k
views
News: The Biostar Swarm: A Visualization
biostars
updated 20 months ago by 44k • written 11.7 years ago by 101k
27
votes
9
replies
4.3k
views
News: OSX 10.11 released 30th Sep will be "rootless"
mac osx
updated 2.1 years ago by 44k • written 9.1 years ago by 13k
25
votes
7
replies
6.5k
views
News: Pubmed Commons : A System That Enables Researchers To Share Their Opinions About Scientific Publications
ncbi pubmed
updated 20 months ago by 44k • written 11.0 years ago by 164k
25
votes
7
replies
3.1k
views
6 follow
News: Who qualifies to be a bioinformatician?
resume bioinformatician vc
updated 2.3 years ago by 44k • written 9.5 years ago by 164k
24
votes
7
replies
4.6k
views
News: #Bioinformatics Crowdcoding
crowd-coding
updated 20 months ago by 44k • written 11.3 years ago by 164k
24
votes
21
replies
8.2k
views
9 follow
News: Misunderstood parameter of NCBI BLAST
blast alignment
updated 17 months ago by 44k • written 6.1 years ago by ★ 3.4k
24
votes
9
replies
679
views
News: Next-Generation Sequencing Data Analysis: A Practical Introduction (September 2-4 in Munich, Germany)
DNAseq Workshop RNAseq
3 months ago by David Langenberger 11k
23
votes
7
replies
4.8k
views
News: Research accounts on GitHub
github git
updated 20 months ago by 44k • written 10.5 years ago by 164k
22
votes
10
replies
5.8k
views
News: samtools/bcftools/htslib 1.0 released
htslib samtools bcftools
updated 2.9 years ago by 44k • written 10.2 years ago by ★ 2.2k
22
votes
3
replies
3.1k
views
News: Biostar: 10,000 Question Milestone
meta
updated 20 months ago by 44k • written 11.4 years ago by 101k
22
votes
9
replies
7.1k
views
News: Epigenetics Workshop - DNA Methylation Data Analysis
bisulfite-sequencing workshop epigenetics
updated 22 months ago by 44k • written 9.4 years ago by 11k
21
votes
7
replies
8.0k
views
News: Survey: Rna-Seq Analysis For Differential Gene/Transcript Expression [Updated With Results]
transcript RNA-seq gene
updated 20 months ago by 44k • written 11.9 years ago by ▴ 250
21
votes
16
replies
6.9k
views
6 follow
News: Pandora's Toolbox - a collection of bioinformatics programs
Assembly alignment RNA-Seq
updated 2.6 years ago by 44k • written 9.8 years ago by ★ 1.1k
21
votes
11
replies
9.8k
views
6 follow
News: NovaSeq from Illumina (updated info)
illumina NovaSeq
updated 18 months ago by 44k • written 7.8 years ago by 146k
20
votes
3
replies
2.8k
views
News: Nature Comment: Core services: Reward bioinformaticians
career-path
updated 2.4 years ago by 44k • written 9.6 years ago by ★ 2.2k
19
votes
4
replies
2.7k
views
News: How to analyze NGS data: An overview of nine different IT solutions
NGS RNA-Seq DNA-Seq
updated 19 months ago by 44k • written 8.0 years ago by 11k
19
votes
11
replies
7.2k
views
News: Solid Software Tools: Denovo Assembly/Xsq Tools Pipeline Mirrored At Biostar
SOLID
updated 20 months ago by 44k • written 12.2 years ago by 101k
18
votes
11
replies
4.3k
views
News: Full Genome Sequencing Service 30x whole human genome sequencing for $3,490 (project cancelled)
genome next-gen-sequencing
updated 2.8 years ago by 44k • written 10.1 years ago by ▴ 100
18
votes
3
replies
2.7k
views
News: LAST CALL: Next-Generation Sequencing Data Analysis: A Practical Introduction (Frankfurt, Germany) - 2 seats left
DNA-Seq NGS Workshop Variant-Calling
updated 2.3 years ago by 44k • written 7.7 years ago by 11k
17
votes
7
replies
9.3k
views
News: Upcoming NGS Workshop: A Beginner's Guide to NGS Data Analysis
workshop Assembly transcriptomics RNA-Seq
updated 2.6 years ago by 44k • written 9.9 years ago by 11k
17
votes
9
replies
4.0k
views
News: My Ncbi Curriculum Vitae Web Application: Sciencv
ncbi
updated 20 months ago by 44k • written 11.1 years ago by 164k
17
votes
6
replies
9.2k
views
News: Final registration deadline: September 15th - Bioinformatics Hands-On NGS Data Analysis Workshops 2014
methylation RNA-seq
updated 20 months ago by 44k • written 10.6 years ago by 11k
16
votes
1
reply
5.1k
views
News: Samtools/htslib/bcftools 1-3 released
htslib samtools bcftools
updated 19 months ago by 44k • written 8.9 years ago by 104k
15
votes
4
replies
2.8k
views
News: Call For Nominations: 2013 Benjamin Franklin Award
benjamin-franklin-award award
updated 20 months ago by 44k • written 11.7 years ago by 164k
15
votes
2
replies
11k
views
News: Breaking News - Illumina MiniSeq
next-gen-sequencing
updated 2.3 years ago by 44k • written 8.8 years ago by ★ 1.3k
15
votes
4
replies
4.9k
views
News: Workshop: Genomic Data Visualization and Interpretation (Berlin, Germany)
dataviz GenVisR next-gen R
updated 18 months ago by 44k • written 7.7 years ago by ★ 2.6k
15
votes
3
replies
7.1k
views
News: Top Bioinformatics Contributions Of 2013
bioinformatics
updated 20 months ago by 44k • written 10.9 years ago by ★ 1.1k
15
votes
18
replies
8.5k
views
6 follow
News: New Free Community Tutorial Website For Bioinformatics Learning
ChIP-seq genome snp RNA-seq
updated 20 months ago by 44k • written 11.3 years ago by ▴ 610
14
votes
4
replies
3.5k
views
News: FULL: NGS Data Analysis Workshop for Beginners in Munich (29 June - 1 Juli 2016)
RNA-Seq next-gen NGS
updated 2.3 years ago by 44k • written 8.7 years ago by 11k
14
votes
5
replies
3.5k
views
News: Science Article On Social Influence Bias On Voting Patterns ("Herding") With Impact On Biostar.
meta biostars
updated 20 months ago by 44k • written 11.2 years ago by 55k
14
votes
1
reply
2.5k
views
News: The Gene Ontology Handbook (open access)
training handbook GO
updated 18 months ago by 44k • written 7.9 years ago by ▴ 740
14
votes
3
replies
3.9k
views
News: Updated: Conference/Symposium/Seminar/Workshop alert 2018-2019
seminar symposium conference
updated 17 months ago by 44k • written 6.4 years ago by 5.9k
14
votes
6
replies
7.3k
views
News: FINAL CALL: NGS Workshop - A Beginner's Guide to NGS Data Analysis (2 last seats)
NGS RNA-Seq workshop
updated 23 months ago by 44k • written 9.3 years ago by 11k
14
votes
11
replies
3.2k
views
6 follow
News: Announcing bioSyntax: Syntax highlighting for biological files
computational-biology
updated 17 months ago by 44k • written 6.8 years ago by ▴ 170
14
votes
2
replies
5.7k
views
News: Open Targets, identifying targets for drug development in the treatment of diseases.
database Drug open-targets
updated 19 months ago by 44k • written 8.4 years ago by ★ 5.2k
1,000 results • Page 1 of 20
Recent Votes
Comment: Finding Differential Phosphosites in TMT Phosphoproteomics Data
Answer: Compare Two Sigle-cell Sample for Differentially Expressed Genes (DEGs). How?
How to Use Biostars, Part-I: Questions, Answers, Comments and Replies
A: How do I ask a question on Biostars?
Answer: How to Use Biostars, Part-I: Questions, Answers, Comments and Replies
Answer: How to Use Biostars, Part-I: Questions, Answers, Comments and Replies
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Comment: Magnesium ion in a post-docking adjustment by dthorbur ★ 2.5k
[`AlphaFold3`](https://alphafoldserver.com/) (assuming you're not at conflict with their terms of use) can handle both ligands and ions. An…
Answer: Compare Two Sigle-cell Sample for Differentially Expressed Genes (DEGs). How? by ATpoint 85k
> But How could I know if the difference comes from sample instead of sequencing runs or cohort-driven batch effect? You cannot. It's pe…
Comment: Comparing GSEA mutant data to wild type by conmul • 0
Sorry that it was unclear in the post. The data is all CRISPR gene effect scores from DepMap. The 'significant genes' as mentioned in the p…
Comment: How to determine whether it is 10x data by king • 0
Thank you for your answer, it's very inspiring.
Comment: Inquiry about depth of coverage and copy number variation by Chen • 0
Thanks Pierre, I was actually thinking about the duplicate PCR reads and didn't explain it properly. I have found a post mentioning that qu…
Comment: Can a read be aligned more than once? by GenoMax 146k
Yes a read can be aligned more than once (I don't specifically know about gam/gaf). It would be called a "multi-mapping" read. You could im…
Comment: Statistical test to be used for dataset by allingt • 0
The choice of test depends on the types of variables involved and the hypothesis you have. But most importantly on the question you want am…
Comment: dittoHeatmap; adding column labels on the heatmap by jared.andrews07 ★ 18k
I'd consider making a [block annotation](https://jokergoo.github.io/ComplexHeatmap-reference/book/heatmap-annotations.html#block-annotation…
Comment: Comparing GSEA mutant data to wild type by allingt • 0
What do you mean by "significant gene"? How did you perform GSEA and on how did you rank your genes for it? From guesswork I might initiall…
Comment: Genes of Interest in a Multi-Tissue Analysis by allingt • 0
The DESeq2 manual tells us that the object class of vst() output is a subclass of RangedSummarizedExperiment. I suspect the methods applica…
Comment: WGCNA: Why are my brown, yellow, and other modules not visible in the gene dendr by allingt • 0
Did you perform blockwise module detection by any chance? Are your results object's contents sorted in blocks?
Comment: Why does WGCNA use weighted correlation instead of Pearson correlation? by allingt • 0
The WGCNA implementation by Langfelder and Horvath provides various correlation methods to create the initial correlation matrix. I don't t…
Comment: dittoHeatmap; adding column labels on the heatmap by Varun Gupta ★ 1.3k
any idea, how can I display the labels Pre and POst on the top of the heatmap? I am looking at complexheatmap package as to how they displa…
Comment: How can I determine the p-value of genes within each identified module in WGCNA? by allingt • 0
What p-value do you mean? When and how did you calculate it?
Answer: What is a genomic range that would almost always get decent WGS coverage but is by i.sudbery 20k
What about some of the well known enhancer regions, the globin locus LCR? Likely to be highly sequenceable, and yet not on exome panels.
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