MARRVEL: Search Result

Human Gene Description (OMIM)

Gene-Phenotype RelationshipsOMIM

Reported Alleles from OMIMSCYL1

Control Population Gene Summary (gnomAD database)

Control Population Gene Summary SCYL1 (ExAC Gene Table)

Allele count
Allele number
Homozygous count
Allele frequency
Gene

Disease Population (Geno2MP database)SCYL1

Reported Alleles from ClinVarSCYL1

Copy Number Variation in Control Population (DGV Database)SCYL1

Position	Size	Type	Subtype	Frequency	Gain	Loss	Sample Size	References	Genes
No data available in table

Gene Function TableSCYL1

Show only best DIOPTv6 score gene

	Homolog	DIOPT Score	Expression	Molecular function	Cellular component	Biological process
Human	SCYL1	NA		cadherin binding involved in cell-cell adhesion	cytoplasm endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus cis-Golgi network cell-cell adherens junction Show 2 more membrane COPI vesicle coat Hide	retrograde vesicle-mediated transport, Golgi to ER
Mouse	Scyl1	12/13	alimentary system nervous system musculoskeletal system connective tissue embryo mesenchyme Show 1 more auditory system Hide	protein binding	cytoplasm COPI vesicle coat	No term based on experiment
Scyl3	1/13	visual system	No term based on experiment	No term based on experiment	No term based on experiment
Zebrafish	scyl1	11/12	No structure expressed in wild-type	No term based on experiment	No term based on experiment	No term based on experiment
scyl3	1/12	unspecified	No term based on experiment	No term based on experiment	No term based on experiment
Drosophila	yata	12/12	Crop Hindgut Malpighian Tubules Fat Body Salivary Gland VirginFemale Spermatheca InseminatedFemale Spermatheca Male Accessory Gland	No term based on experiment	No term based on experiment	No term based on experiment
CG1344	1/12	Eye Brain Thoracic-Abdominal Ganglion Crop Hindgut Fat Body Salivary Gland Heart Ovary VirginFemale Spermatheca InseminatedFemale Spermatheca Male Accessory Gland	No term based on experiment	No term based on experiment	No term based on experiment
C Elegans	W07G4.3	9/12		No term based on experiment	No term based on experiment	No term based on experiment
Budding Yeast	CEX1	10/11		tRNA binding	nuclear pore cytoplasm	tRNA export from nucleus
Fission Yeast	ppk3	7/8		No term based on experiment	Golgi apparatus	No term based on experiment

Protein Atlas
GTEx

Organ	Expression Level
adipose tissue	not detected
adrenal gland	not detected
appendix	not detected
bone marrow	not detected
breast	not detected
bronchus	not detected
caudate	not detected
cerebellum	low
cerebral cortex	low
cervix, uterine	not detected
colon	medium
duodenum	not detected
endometrium	low
epididymis	not detected
esophagus	not detected
fallopian tube	not detected
gallbladder	not detected
heart muscle	not detected
hippocampus	not detected
kidney	not detected
liver	not detected
lung	low
lymph node	not detected
nasopharynx	not detected
oral mucosa	not detected
ovary	low
pancreas	medium
parathyroid gland	not detected
placenta	low
prostate	not detected
rectum	not detected
salivary gland	not detected
seminal vesicle	not detected
skeletal muscle	not detected
skin	not detected
small intestine	not detected
smooth muscle	low
soft tissue	not detected
spleen	not detected
stomach	medium
testis	low
thyroid gland	low
tonsil	low
urinary bladder	not detected
vagina	not detected

FlyAtlas Organ/Tissue Expression, larval vs. adult

< 10

< 100

< 500

< 1000

>= 1000

	Adult	Larval
Head	77.9	NA
Eye	67.1	NA
Brain	59.4	NA
Thoracic-Abdominal Ganglion	59.4	NA
Crop	117.4	NA
Midgut	89.9	106.8
Hindgut	116.1	96.6
Malpighian Tubules	128.5	105.4
Fat Body	103.0	88.9
Salivary Gland	335.0	291.9
Heart	72.5	NA
Carcass	93.7	103.0
Ovary	81.6	NA
Testis	42.1	NA
VirginFemale Spermatheca	223.7	NA
InseminatedFemale Spermatheca	224.9	NA
Male Accessory Gland	535.2	NA
Central Nervous System	NA	62.2
Trachea	NA	80.9