The NIH HPC group plans, manages and supports high-performance computing systems specifically for use by the intramural NIH community. These systems include Biowulf, a 105,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Monday, September 30th, 2024
utilization graph
Last 24 hrs
93,006 jobs submitted
56,496 jobs completed
3,353,773 CPU hrs used
25 NIH Institutes
299 Principal Investigators
629 users

Announcements
Recent Papers that used Biowulf & HPC Resources

Automated Classification of Multi-parametric Body MRI Series
Kim B, Mathai TS, Helm K, Summers RM
IEEE International Symposium on Biomedical Imaging , https://doi.org/10.1109/ISBI56570.2024.10635686 (2024)


σ28-dependent small RNA regulation of flagella biosynthesis
Melamed, S; Zhang, A; Jarnik, M et al.
Elife , DOI://10.7554/eLife.87151 (2023)


PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma
Keggenhoff, FL; Castven, D; Becker, D et al.
Gut , DOI://10.1136/gutjnl-2023-331237 (2024)


Structure of Amyloid Peptide Ribbons Characterized by Electron Microscopy, Atomic Force Microscopy, and Solid-State Nuclear Magnetic Resonance
Thurber, KR; Yau, WM; Tycko, R; ,
J Phys Chem B , DOI://10.1021/acs.jpcb.3c07867 (2024)


Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS
Cetin Gedik, K; Ortega-Villa, AM; Materne, G et al.
Ann Rheum Dis , DOI://10.1136/ard-2023-225463 (2024)


Elementary intracellular Ca signals approximated as a transition of release channel system from a metastable state
Veron, G; Maltsev, VA; Stern, MD; Maltsev, AV; ,
J Appl Phys , DOI://10.1063/5.0151255 (2023)


A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics
Hoang, DT; Dinstag, G; Shulman, ED et al.
Nat Cancer , DOI://10.1038/s43018-024-00793-2 (2024)


A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus
Oliveira, C; Temesgen-Oyelakin, Y; Naqi, M et al.
Arthritis Rheumatol , DOI://10.1002/art.42925 (2024)