Directory structure
-
Run_SCENIC
-- inferring regulons using SCENIC -
Post_SCENIC
-- scripts for updating regulons based on frequency across iterations; and for identifying differential regulons: each cancer vs others (tumor cells only), and each tumor vs CNC. -
Diff_TFs_ATAC_based
-- identifying differential TFs: each cancer vs others (tumor cells only), and each tumor vs CNC. -
ENCODE_validation
-- validation of regulons' targets using ChIP-seq data (ENCODE).