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HussainAther committed Apr 23, 2019
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18 changes: 15 additions & 3 deletions biophysics/secondarystructure.py
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"""
RNA has some of the properties of both DNA and proteins. It has the same information storage capability as DNA due to its sequence of nucleotides. But its ability to form 3D structures allows it to have enzymatic properties like those of proteins. We call the linear polynucleotide chain the primary structure of RNA; the intra-molecular base-pairing is the secondary structure.
RNA has some of the properties of both DNA and proteins. It has the same
information storage capability as DNA due to its sequence of nucleotides.
But its ability to form 3D structures allows it to have enzymatic properties
like those of proteins. We call the linear polynucleotide chain the primary
structure of RNA; the intra-molecular base-pairing is the secondary structure.
Secondary structures are important for RNA functions. For example, tRNA molecules all form similar structures (a characteristic "clover-leaf", one branch of which is the "anticodon loop", which pairs with a codon as part of the process of translating a messenger RNA into protein). Overall, the structures are critical to their function.
Secondary structures are important for RNA functions. For example, tRNA
molecules all form similar structures (a characteristic "clover-leaf",
one branch of which is the "anticodon loop", which pairs with a codon as
part of the process of translating a messenger RNA into protein). Overall,
the structures are critical to their function.
Of all possible 16 base-pairings, 6 of them are considered stable. The Watson-Crick base pairs, C-G and A-U, form stable base pairs with each other through the creation of hydrogen bonds between donor and acceptor sites on the bases. In addition, the G-U wobble pair is weaker but still stable. Other bases also pair sometimes, especially if chemically modified.
Of all possible 16 base-pairings, 6 of them are considered stable. The Watson-Crick
base pairs, C-G and A-U, form stable base pairs with each other through
the creation of hydrogen bonds between donor and acceptor sites on the bases.
In addition, the G-U wobble pair is weaker but still stable. Other bases also
pair sometimes, especially if chemically modified.
"""

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