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Gavin J. Becker, Tim D. Hewitson, Animal models of chronic kidney disease: useful but not perfect, Nephrology Dialysis Transplantation, Volume 28, Issue 10, October 2013, Pages 2432–2438, https://doi.org/10.1093/ndt/gft071
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Abstract
Animal models of chronic kidney disease (CKD) approximate the human condition and are keys to understanding its pathogenesis and to developing rational treatment strategies. The ethical use of animals requires a detailed understanding of the strengths and limitations of each species and the disease model, and the way in which findings can be translated from animals to humans. While not perfect, the careful use of animal experiments offers the opportunity to examine individual mechanisms in an accelerated time frame.
© The Author 2013. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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