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One-year hypertension incidence and its predictors in a working population: the IHPAF study

Journal of Human Hypertension volume 18, pages 487–494 (2004)Cite this article

Abstract

The aims of our study were: (i) to estimate the yearly incidence rates based on one vs two visits in a working population and (ii) to identify incident hypertension modifiable risk factors. A total of 21 566 normotensive subjects were included in a 1-year cohort study. Blood pressure (BP) levels at inclusion and at the second year screening were measured on the basis of two visits, that is, if BP was over 140/90 mmHg in untreated subjects, they were invited to a control visit 1 month later. Height and weight were measured and behavioural risk factors were collected. Among the 17 465 subjects who completed the entire protocol (9691 men and 7774 women), 17 026 remained normotensive at a 1-year interval and 439 (325 men and 114 women) became hypertensive. Crude yearly incidence rates based on one visit were 6.21% in men and 3.06% in women, compared with 3.04% in men and 1.34% in women when incidence rates were based on two visits, a more than twofold difference. Age and body mass index at baseline were the two major independent determinants of incident hypertension in both genders. Smoking and alcohol consumption were significant risk factors in men but not in women, and a low educational level only in women. BP measurement on separate occasions is necessary to avoid overestimation of incidence. Weight in both genders and alcohol consumption in men were the main modifiable predictors of hypertension.

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Acknowledgements

This study was undertaken under the auspices of the French Society of Hypertension and its epidemiology group. The following pharmaceutical companies have supported the activity of the group and this study: Astra, Bristol-Myers-Squibb, Debat Cardio, Hoeschst-Houde, Information Servier, Lipha, Merck Sharp & Dohme Chibret, Roussel, Rhône Poulenc Rorer, Wyeth-Lederle, Zeneca, and Glaxo Welcome. We thank the staff of the work sites without whom this work would not have been possible.

Samia Radi was supported by a combined grant of the French Society of Hypertension and Sanofi-Synthélabo.

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Author notes

  1. S Radi, T Lang, V Lauwers-Cancès, G Chatellier, J-P Fauvel, L Larabi and R De Gaudemaris: IHPAF working physicians: Drs Agopian B, Amoureux C, Arsac L, Barthelemy C, Begnard N, Belville MR, Bidault M, Boijoux C, Chamard F, Chamot A, Chanut B, Charrière, Chebli H, Cholley N, Combre C, Combre MC, Costa C, De Dreuzy C, Decatoire J, Defawe B, Dischant M, Duquesne D, Elter I, Filliard E, Fortier I, Gamot, Grasset J, Guiret A, Hage H, Hinard ML, Hoorelbeke A, Lafragette A, Langlois L, Laplaiche N, Lariviere D, Marlin F, Michel-Panichi C, Nghiem ZH, Paquette C, Pasquet B, Picart S, Piotte S, Portal S, Poudevigne A, Ramambason H, Rodallec D, Roux AM, Royon J, Sailly E, Servagent JJ, Solanet J, Stern M, Wolff R, Zerbib MH.Epidemiology group of the French Society of Hypertension: Mallion JM, Ducimetière P, Plouin PF, Cambou JP.

Authors and Affiliations

  1. Département d'Epidémiologie et de Santé Publique, Unité INSERM 558, Faculté de Médecine, Toulouse, Cedex, France

    S Radi, T Lang & V Lauwers-Cancès

  2. Département d'Informatique Hospitalière, Hôpital Européen Georges Pompidou, Paris, France

    G Chatellier

  3. Département de Néphrologie et Hypertension, Hôpital E. Herriot, Lyon, France

    J-P Fauvel

  4. Service de Médecine et Santé au Travail, CHU de Grenoble, Grenoble, Cedex, France

    L Larabi & R De Gaudemaris

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  1. S Radi
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  6. L Larabi
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Correspondence to T Lang.

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Radi, S., Lang, T., Lauwers-Cancès, V. et al. One-year hypertension incidence and its predictors in a working population: the IHPAF study. J Hum Hypertens 18, 487–494 (2004). https://doi.org/10.1038/sj.jhh.1001682

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