Search

Search Results

1. Transgenesis in Worms: Candidates for an Ideal Model

   Abstract

   Transgenesis is an important and often irreplaceable method to study numerous processes of animal life. To create animal transgenic lines, it...

   I. S. Sukhikh, M. Yu. Biryukov, A. G. Blinov in Molecular Biology

   Article 09 December 2022

2. Transgenesis Methods and Protocols

   This detailed volume focuses on genotyping and validation in addition to information on how to produce gene edited cells and animals for research....

   Thomas L. Saunders in Methods in Molecular Biology

   Book 2023
   

3. Improving transgenesis in zebrafish

   Alexandra Le Bras in Lab Animal

   Article 01 August 2024

4. Evolution of Transgenic Technology: From Random Transgenesis to Precise Genome Editing

   New techniques in molecular biology help us for better understanding of biological processes. As biologists we resort to powerful approaches for...

   Shrabani Saugandhika, Nishkarsh Jain in Sustainable Agriculture Reviews

   Chapter 2024
   

5. Transgenesis and Biopharming

   Transgenesis is the process of introducing foreign or exogenous DNA into an animal’s genome. The steps include knockout or knockin of gene. Outline...

   Aruna Pal in Protocols in Advanced Genomics and Allied Techniques

   Protocol 2022
   

6. Transgenesis and Genome Engineering: A Historical Review

   Our ability to modify DNA molecules and to introduce them into mammalian cells or embryos almost appears in parallel, starting from the 1970s of the...

   Lluis Montoliu in Transgenesis

   Protocol 2023
   

7. Mutagenesis and Transgenesis in Plant Breeding

   Mutagenesis gives an avenue of possibilities for developing improved cultivars in crops with limited or no variability in a specific trait....

   Anurag Tripathi, Sudhir Kumar, ... Pradipta Ranjan Pradhan in Advanced Crop Improvement, Volume 1

   Chapter 2023
   

8. Validation of reliable safe harbor locus for efficient porcine transgenesis

   Transgenic technology is now widely used in biomedical and agricultural fields. Transgenesis is commonly achieved through random integration which...

   Xiang Ma, Weijun Zeng, ... Dong Niu in Functional & Integrative Genomics

   Article 12 April 2022
   

9. Animal Transgenesis and Cloning: Combined Development and Future Perspectives

   The revolution in animal transgenesis began in 1981 and continues to become more efficient, cheaper, and faster to perform. New genome editing...

   Melissa S. Yamashita, Eduardo O. Melo in Somatic Cell Nuclear Transfer Technology

   Protocol 2023
   

10. Transgenesis: In the Drug Discovery Process, Including Target Identification and Target Validation

    Transgenic targeting is the most dependable method for mouse transgenesis because it produces predictable transgene expression patterns. This method...

    Aniruddha Mukherjee, Susovan Das, ... Sugato Banerjee in Concepts in Pharmaceutical Biotechnology and Drug Development

    Chapter 2024
    

11. Axolotl Transgenesis via Injection of I-SceI Meganuclease or Tol2 Transposon System

    The axolotlAxolotls (Ambystoma mexicanum ) has been widely used as an animal model for studying development and regeneration. In recent decades, the...

    Maritta Schuez, Tatiana Sandoval-Guzmán in Salamanders

    Protocol 2023
    

12. Transgenesis in parasitic helminths: a brief history and prospects for the future

    Helminth infections impact the health of hundreds of millions of persons globally and also cause important economic losses in livestock farming....

    M. J. Quinzo, M. J. Perteguer, ... J. Sotillo in Parasites & Vectors

    Article Open access 28 March 2022
    

13. Tackling Tissue Macrophage Heterogeneity by SplitCre Transgenesis

    Macrophages represent a broad spectrum of distinct, but closely related tissue-resident immune cells. This presents a major challenge for the study...

    Sigalit Boura-Halfon, Rebecca Haffner-Krausz, ... Steffen Jung in Tissue-Resident Macrophages

    Protocol 2024
    

14. Xenopus Transgenesis Using the pGateway System

    Transgenic approaches using I-SceI are powerful genome modification methods for creating heritable modifications in eukaryotic genomes. Such...

    Liliya Nazlamova in DNA Manipulation and Analysis

    Protocol 2023
    

15. Application of transposon systems in the transgenesis of bovine somatic and germ cells

    Background

    Several DNA transposons including PiggyBac (PB), Sleeping Beauty (SB), and Tol2 have been applied as effective means for of transgenesis...

    Dong-Hyeok Kwon, Gyeong-Min Gim, ... Goo Jang in BMC Veterinary Research

    Article Open access 27 April 2022
    

16. Transgenesis in Plants: Principle and Methods

    The human population has reached 7.8 billion by 2020 and is estimated to reach 9.9 billion by the end of 2050 which is nearly 25% increase in total...

    Pradeep Kumar Singh, Pankaj Singh, ... Ram Lakhan Singh in Plant Genomics for Sustainable Agriculture

    Chapter 2022
    

17. Random Integration Transgenesis in a Free-Living Regenerative Flatworm Macrostomum lignano

    Regeneration-capable flatworms are highly informative research models to study the mechanisms of stem cell regulation, regeneration, and tissue...

    Jakub Wudarski, Kirill Ustyantsev, ... Eugene Berezikov in Whole-Body Regeneration

    Protocol Open access 2022
    

18. Efficient targeted transgenesis of large donor DNA into multiple mouse genetic backgrounds using bacteriophage Bxb1 integrase

    The development of mouse models of human disease and synthetic biology research by targeted transgenesis of large DNA constructs represent a...

    Benjamin E. Low, Vishnu Hosur, ... Michael V. Wiles in Scientific Reports

    Article Open access 31 March 2022
    

19. Practical Application of the 3Rs in Rodent Transgenesis

    The principles of the 3Rs (replace, reduce, refine), as originally published by Russell and Burch, are internationally acclaimed guidelines for...

    Thorsten Buch, Boris Jerchow, Branko Zevnik in Transgenesis

    Protocol 2023
    

20. Rat Embryonic Stem Cell Transgenesis

    The availability of reliable germline competent rat embryonic stem cell (ESC) lines that can be genetically manipulated provides an important tool...

    Elizabeth C. Bryda, Hongsheng Men, Barbara J. Stone in Transgenesis

    Protocol 2023