Search
Search Results
-
Metabolic profiling of galectin-1 and galectin-3: a cross-sectional, multi-omics, association study
ObjectivesExperimental studies indicate a role for galectin-1 and galectin-3 in metabolic disease, but clinical evidence from larger populations is...
-
Emerging Roles of Galectin-3 in Pulmonary Diseases
Galectin-3 is a multifunctional protein that is involved in various physiological and pathological events. Emerging evidence suggests that galectin-3...
-
TIM-3 on myeloid cells promotes pulmonary inflammation through increased production of galectin-3
T cell immunoglobulin and mucin-containing molecule 3 (TIM-3) exhibits unique, cell type- and context-dependent characteristics and functions. Here,...
-
Galectin-3 levels in children with cystic fibrosis
Cystic fibrosis (CF) is a multisystemic disease in which airway obstruction, infection, and inflammation play a critical role in the pathogenesis and...
-
Elevated galectin-3 levels detected in women with hyperglycemia during early and mid-pregnancy antagonizes high glucose − induced trophoblast cells apoptosis via galectin-3/foxc1 pathway
ObjectiveThis study was to evaluate plasma galectin-3 levels from early pregnancy to delivery and explore the effects of galectin-3 on the function...
-
Galectin-3: action and clinical utility in chronic kidney disease
Chronic kidney disease is a significant cause of morbidity and mortality worldwide. In recent years, Galectin-3 has been put forward as a potential...
-
Association between sleep patterns and galectin-3 in a Chinese community population
BackgroundIrregular sleep patterns have been associated with inflammation. Galectin-3, a novel biomarker, plays an important role in inflammation. We...
-
Pectin: Health-promoting properties as a natural galectin-3 inhibitor
Galectin-3 has a variety of important pathophysiological significance in the human body. Much evidence shows that the abnormal expression of...
-
Mediating effect of vascular calcification in galectin-3-related mortality in hemodialysis patients
Galectin-3 levels have been studied as a potential biomarker for predicting cardiovascular (CV) risk and mortality in hemodialysis (HD) patients....
-
The silent predictors: exploring galectin-3 and Irisin’s tale in severe COVID-19
ObjectiveThis study aimed to evaluate the roles of galectin-3 and irisin as biomarkers in predicting severe outcomes in COVID-19 patients.
...
-
Role of Galectin-3 in intervertebral disc degeneration: an experimental study
BackgroundThis study investigated the role of Galectin-3 in the degeneration of intervertebral disc cartilage.
MethodsThe patients who underwent...
-
Transcriptional upregulation of galectin-3 in multiple sclerosis
Multiple sclerosis (MS) is an autoimmune, demyelinating disorder of the central nervous system (CNS) affecting approximately 2.5 million people...
-
Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure
Respiratory infection by Pseudomonas aeruginosa , common in hospitalized immunocompromised and immunocompetent ventilated patients, can be...
-
Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in mice
BackgroundIn the context of spinal cord injury (SCI), infiltrating macrophages assume prominence as the primary inflammatory cells within the lesion...
-
Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
BackgroundHigh infiltration of tumor-associated macrophages (TAMs) is associated with tumor promotion and immunosuppression. The triggering receptor...
-
Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells
Intracellular vesicle transport is essential for cellular homeostasis and is partially mediated by SNARE proteins. Endosomal trafficking to the...
-
Galectin-3 and cancer immunotherapy: a glycobiological rationale to overcome tumor immune escape
Immunotherapy with checkpoint inhibitors (ICIs) has radically changed the landscape of therapeutic opportunities in oncology, but much still needs to...
-
Relationship between galectin-3 level and disease activity in ankylosing spondylitis patients
Background and aimsAnkylosing spondylitis (AS) is a chronic inflammatory disease that chiefly affects the sacroiliac joints and the spine....
-
Galectin-3 and its correlation with carotid ultrasound in rheumatoid arthritis patients
BackgroundRheumatoid arthritis (RA) is a chronic inflammatory disease resulting in disability as well as joint damage. Early diagnosis and treatment...
-
A critical influence of HIF-1 on MMP-9 and Galectin-3 in oral lichen planus
ObjectiveOral lichen planus carries a risk for malignancy. The pathogenesis of the disease is mediated by various inflammatory mediators. Several...
