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Page 1
Showing results for comet study authors
Search for Comepa Study Authors instead (1 results)
Measuring DNA modifications with the comet assay: a compendium of protocols.
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo' CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A. Collins A, et al. Nat Protoc. 2023 Mar;18(3):929-989. doi: 10.1038/s41596-022-00754-y. Epub 2023 Jan 27. Nat Protoc. 2023. PMID: 36707722 Free PMC article. Review.
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. ...Various applications of the comet assay have been validated by research groups in academia, industry and regulatory agencies, and …
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. ...Var …
Comet assay and hormesis.
Calabrese EJ, Selby PB. Calabrese EJ, et al. Environ Pollut. 2024 Jan 15;341:122929. doi: 10.1016/j.envpol.2023.122929. Epub 2023 Nov 16. Environ Pollut. 2024. PMID: 37979647 Review.
The paper provides the first assessment of the occurrence of hormetic dose responses using the Comet assay, a genotoxic assay. Using a priori evaluative criteria based on the Hormetic Database on peer-reviewed comet assay experimental findings, …
The paper provides the first assessment of the occurrence of hormetic dose responses using the Comet assay, a genotoxic ass …
Genotoxicity of Silver Nanoparticles.
Rodriguez-Garraus A, Azqueta A, Vettorazzi A, López de Cerain A. Rodriguez-Garraus A, et al. Nanomaterials (Basel). 2020 Jan 31;10(2):251. doi: 10.3390/nano10020251. Nanomaterials (Basel). 2020. PMID: 32023837 Free PMC article. Review.
However, a higher proportion of positive results was obtained in the in vitro studies. Some authors observed that coating and size had an effect on both in vitro and in vivo results. None of the studies included a complete battery of assays, as recommended by …
However, a higher proportion of positive results was obtained in the in vitro studies. Some authors observed that coating and …
The Comet Assay in Drosophila: A Tool to Study Interactions between DNA Repair Systems in DNA Damage Responses In Vivo and Ex Vivo.
Rodríguez R, Gaivão I, Aguado L, Espina M, García J, Martínez-Camblor P, Sierra LM. Rodríguez R, et al. Cells. 2023 Jul 31;12(15):1979. doi: 10.3390/cells12151979. Cells. 2023. PMID: 37566058 Free PMC article.
The comet assay in Drosophila has been used in the last few years to study DNA damage responses (DDR) in different repair-mutant strains and to compare them to analyze DNA repair. We have used this approach to study interactions between DNA repair path …
The comet assay in Drosophila has been used in the last few years to study DNA damage responses (DDR) in different repa …
Genotoxicity study of 2-methoxyethanol and benzalkonium chloride through Comet assay using 3D cultured HepG2 cells.
Lim C, Shin K, Seo D. Lim C, et al. Environ Anal Health Toxicol. 2022 Dec;37(4):e2022031-0. doi: 10.5620/eaht.2022031. Epub 2022 Oct 28. Environ Anal Health Toxicol. 2022. PMID: 36916044 Free PMC article.
The micronucleus assay and the comet assay in 3D culture system of human-derived cells is considered as the most applicable practical measures at this stage. ...Though 2-methoxyethanol is positive in in vivo comet assay and in vitro mammalian ch …
The micronucleus assay and the comet assay in 3D culture system of human-derived cells is considered as the most applic …
The Comet assay in insects--Status, prospects and benefits for science.
Augustyniak M, Gladysz M, Dziewięcka M. Augustyniak M, et al. Mutat Res Rev Mutat Res. 2016 Jan-Mar;767:67-76. doi: 10.1016/j.mrrev.2015.09.001. Epub 2015 Nov 10. Mutat Res Rev Mutat Res. 2016. PMID: 27036067 Review.
Since then, the interest in the application of the Comet assay to studies of insects has been rapidly increasing. Many authors see substantial potential in the use of the Comet assay in D. melanogaster for medical toxicology studies …
Since then, the interest in the application of the Comet assay to studies of insects has been rapidly increasing. Many …
A review of the genotoxicity of the industrial chemical cumene.
Gollapudi BB, Williams AL, Bus JS. Gollapudi BB, et al. Mutat Res Rev Mutat Res. 2021 Jan-Jun;787:108364. doi: 10.1016/j.mrrev.2021.108364. Epub 2021 Jan 5. Mutat Res Rev Mutat Res. 2021. PMID: 34083043 Free article. Review.
In the primary rat hepatocyte cultures, cumene induced unscheduled DNA synthesis in one study but this response could not be reproduced in an independent study using a similar protocol. ...The weight of the evidence (WoE) from multiple in vivo studies indicat …
In the primary rat hepatocyte cultures, cumene induced unscheduled DNA synthesis in one study but this response could not be reproduc …
Calibration of the comet assay using ionising radiation.
Brunborg G, Eide DM, Graupner A, Gutzkow K, Shaposhnikov S, Kruszewski M, Sirota N, Jones GDD, Koppen G, Vanhavere F, Møller P, Stetina R, Dahl H, Collins A. Brunborg G, et al. Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 36669811 Free article.
Several trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a referenc …
Several trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving …
Applications of CometChip for Environmental Health Studies.
Chao C, Engelward BP. Chao C, et al. Chem Res Toxicol. 2020 Jul 20;33(7):1528-1538. doi: 10.1021/acs.chemrestox.9b00393. Epub 2020 Jun 10. Chem Res Toxicol. 2020. PMID: 32519858 Free PMC article. Review.
Cancer can take years to develop following chemical exposure; however, one way to predict carcinogenicity in a more practical time frame is by studying the chemical's ability to induce DNA damage. The comet assay (or single-cell gel electrophoresis assay …
Cancer can take years to develop following chemical exposure; however, one way to predict carcinogenicity in a more practical time frame is …
Toxicological assessment of minoxidil: A drug with therapeutic potential besides alopecia.
da Silva Prado L, Grivicich I, Miri JM, Charão MF, Bonfada A, Endres da Rocha G, Bondan da Silva J, Menezes Boaretto FB, Garcia ALH, da Silva J, Picada JN. da Silva Prado L, et al. Food Chem Toxicol. 2023 Dec;182:114211. doi: 10.1016/j.fct.2023.114211. Epub 2023 Nov 23. Food Chem Toxicol. 2023. PMID: 38007212
This study aimed to access cytotoxic, genotoxic, and mutagenic properties of minoxidil using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) assay, comet assay, and micronucleus test in mouse fibroblast (L929) cells and its poin …
This study aimed to access cytotoxic, genotoxic, and mutagenic properties of minoxidil using the 3-[4,5-dimethylthiazol-2-yl]-2,5-dip …
2,208 results