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Page 1
Dynamics of Recent Thymic Emigrants in Young Adult Mice.
van Hoeven V, Drylewicz J, Westera L, den Braber I, Mugwagwa T, Tesselaar K, Borghans JAM, de Boer RJ. van Hoeven V, et al. Among authors: den braber i. Front Immunol. 2017 Aug 7;8:933. doi: 10.3389/fimmu.2017.00933. eCollection 2017. Front Immunol. 2017. PMID: 28824653 Free PMC article.
Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis.
van Herwijnen MJ, Wieten L, van der Zee R, van Kooten PJ, Wagenaar-Hilbers JP, Hoek A, den Braber I, Anderton SM, Singh M, Meiring HD, van Els CA, van Eden W, Broere F. van Herwijnen MJ, et al. Among authors: den braber i. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14134-9. doi: 10.1073/pnas.1206803109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891339 Free PMC article.
In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.
Pillay J, den Braber I, Vrisekoop N, Kwast LM, de Boer RJ, Borghans JA, Tesselaar K, Koenderman L. Pillay J, et al. Among authors: den braber i. Blood. 2010 Jul 29;116(4):625-7. doi: 10.1182/blood-2010-01-259028. Epub 2010 Apr 21. Blood. 2010. PMID: 20410504 Free article. Clinical Trial.
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EH, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AF, Ackermans MT, Miedema F, Borghans JA, de Boer RJ, Tesselaar K. den Braber I, et al. Immunity. 2012 Feb 24;36(2):288-97. doi: 10.1016/j.immuni.2012.02.006. Immunity. 2012. PMID: 22365666 Free article.
Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans.
Westera L, Drylewicz J, den Braber I, Mugwagwa T, van der Maas I, Kwast L, Volman T, van de Weg-Schrijver EH, Bartha I, Spierenburg G, Gaiser K, Ackermans MT, Asquith B, de Boer RJ, Tesselaar K, Borghans JA. Westera L, et al. Among authors: den braber i. Blood. 2013 Sep 26;122(13):2205-12. doi: 10.1182/blood-2013-03-488411. Epub 2013 Aug 14. Blood. 2013. PMID: 23945154 Free article.
Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool.
Vrisekoop N, den Braber I, de Boer AB, Ruiter AF, Ackermans MT, van der Crabben SN, Schrijver EH, Spierenburg G, Sauerwein HP, Hazenberg MD, de Boer RJ, Miedema F, Borghans JA, Tesselaar K. Vrisekoop N, et al. Among authors: den braber i. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6115-20. doi: 10.1073/pnas.0709713105. Epub 2008 Apr 17. Proc Natl Acad Sci U S A. 2008. PMID: 18420820 Free PMC article.